NICU Copilot

Neonatal Hyperbilirubinemia

Most common reason for readmission. Use hour-specific nomogram (Bhutani / 2022 AAP).

All references

Key points

  • Phototherapy and exchange thresholds per 2022 AAP nomogram.
  • Risk factors: prematurity, hemolysis, bruising, exclusive breastfeeding.
  • Watch for bilirubin neurotoxicity / kernicterus.

Pitfalls

  • Direct hyperbili always abnormal — workup for cholestasis.
  • Don't rely solely on visual estimation.

Ask the Copilot

  • — Phototherapy threshold at 36+0 GA, 48h old, 14 mg/dL?

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